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Christine E McLaren Selected Research

Ferritins (Ferritin)

1/2019Bivariate mixture models for the joint distribution of repeated serum ferritin and transferrin saturation measured 12 years apart in a cohort of healthy middle-aged Australians.
4/2017HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: A genotype-stratified cohort study of hemochromatosis in Australian women.
4/2015Natural history of HFE simple heterozygosity for C282Y and H63D: a prospective 12-year study.
7/2013HFE mutations in Caucasian participants of the Hemochromatosis and Iron Overload Screening study with serum ferritin level <1000 µg/L.
7/2013Association between celiac disease and iron deficiency in Caucasians, but not non-Caucasians.
6/2013Telomere length and elevated iron: the influence of phenotype and HFE genotype.
6/2012Probability of C282Y homozygosity decreases as liver transaminase activities increase in participants with hyperferritinemia in the hemochromatosis and iron overload screening study.
1/2012Associations between single nucleotide polymorphisms in iron-related genes and iron status in multiethnic populations.
3/2011Genome-wide association study identifies genetic loci associated with iron deficiency.
9/2010HFE Cys282Tyr homozygotes with serum ferritin concentrations below 1000 microg/L are at low risk of hemochromatosis.
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Christine E McLaren Research Topics

Disease

36Hemochromatosis (Bronze Diabetes)
11/2020 - 02/2003
35Iron Overload
11/2020 - 02/2003
10Neoplasms (Cancer)
01/2020 - 03/2002
8Adenoma (Adenomas)
01/2020 - 06/2008
7Hyperferritinemia
08/2018 - 02/2007
4Fibrosis (Cirrhosis)
08/2018 - 01/2008
4Liver Diseases (Liver Disease)
05/2017 - 08/2007
4Breast Neoplasms (Breast Cancer)
04/2017 - 10/2003
3Iron Deficiencies
07/2013 - 03/2011
2Sepsis (Septicemia)
09/2013 - 07/2013
2Infections
09/2013 - 07/2013
2Fetomaternal Transfusion
09/2013 - 07/2013
2Ototoxicity
10/2010 - 12/2008
2Fatigue
09/2010 - 01/2008
2Arthritis (Polyarthritis)
09/2010 - 01/2008
2Adenomatous Polyps
12/2008 - 06/2008
2Skin Neoplasms (Skin Cancer)
12/2004 - 01/2003
2Asthma (Bronchial Asthma)
06/2004 - 10/2002
1Polyps
01/2020
1Colorectal Neoplasms (Colorectal Cancer)
01/2020
1Fatty Liver
08/2018
1Hemorrhage
01/2018
1Porphyria Cutanea Tarda
01/2016
1type 2 Rhizomelic chondrodysplasia punctata
08/2015
1Melanoma (Melanoma, Malignant)
05/2014
1Nevus (Nevi)
05/2014
1Residual Neoplasm
02/2014
1Cardiovascular Diseases (Cardiovascular Disease)
01/2014
1Prostatic Neoplasms (Prostate Cancer)
01/2014
1Atrophy
12/2013
1Uterine Cervical Neoplasms (Cancer of the Cervix)
03/2013
1Hyperthermia
03/2013
1Obesity
10/2012
1Noninfiltrating Intraductal Carcinoma (DCIS)
06/2011
1Hepatomegaly
09/2010
1Diabetes Mellitus
09/2010
1Hearing Loss (Hearing Impairment)
12/2008
1Hepatocellular Carcinoma (Hepatoma)
01/2008
1Joint Diseases (Joint Disease)
01/2008
1Liver Cirrhosis (Hepatic Cirrhosis)
01/2008
1Confusion (Bewilderment)
11/2007
1Colonic Polyps
01/2006
1Colonic Neoplasms (Colon Cancer)
01/2006
1Actinic Keratosis
12/2004
1Head and Neck Neoplasms (Head and Neck Cancer)
10/2004

Drug/Important Bio-Agent (IBA)

29IronIBA
11/2020 - 02/2003
21Ferritins (Ferritin)IBA
01/2019 - 01/2005
16Transferrin (beta 2 Transferrin)IBA
01/2019 - 01/2005
7Biomarkers (Surrogate Marker)IBA
04/2017 - 10/2003
5Eflornithine (Ornidyl)FDA Link
10/2012 - 06/2008
5Sulindac (Copal)FDA LinkGeneric
10/2010 - 06/2008
4DNA (Deoxyribonucleic Acid)IBA
08/2015 - 02/2003
4Pharmaceutical PreparationsIBA
09/2013 - 10/2002
3AcyltransferasesIBA
11/2020 - 08/2015
3PolyaminesIBA
10/2012 - 09/2010
2Hemochromatosis ProteinIBA
01/2019 - 04/2015
2Hemoglobins (Hemoglobin)IBA
01/2018 - 10/2007
2metal transporting protein 1 (ferroportin)IBA
01/2018 - 05/2007
2LipidsIBA
01/2018 - 05/2014
2Equilibrative Nucleoside Transporter 1IBA
09/2013 - 07/2013
2Transaminases (Aminotransferases)IBA
06/2012 - 01/2008
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2011 - 10/2003
2Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
10/2010 - 06/2008
2PlacebosIBA
12/2008 - 06/2008
1Metformin (Glucophage)FDA LinkGeneric
01/2020
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
08/2018
1Alanine Transaminase (SGPT)IBA
08/2018
1HepcidinsIBA
01/2018
1deoxyhemoglobinIBA
01/2018
1Hormones (Hormone)IBA
01/2018
1Proteins (Proteins, Gene)FDA Link
01/2018
1Indicators and Reagents (Reagents)IBA
05/2017
1TamoxifenFDA LinkGeneric
04/2017
1Small Interfering RNA (siRNA)IBA
08/2015
1Lovastatin (Mevacor)FDA LinkGeneric
05/2014
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2014
1Doxorubicin (Adriamycin)FDA LinkGeneric
12/2013
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
12/2013
1taxaneIBA
12/2013
1OrnithineIBA
10/2010
1Dinoprostone (PGE2)FDA Link
09/2010
1EnzymesIBA
09/2010
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2010
1Carrier Proteins (Binding Protein)IBA
03/2009
1Heme (Haem)IBA
03/2009
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
03/2009
1Immunomodulating AgentsIBA
01/2006
1Levamisole (Decaris)FDA Link
01/2006
1Biological ProductsIBA
12/2004

Therapy/Procedure

5Chemoprevention
01/2014 - 01/2003
3Therapeutics
01/2014 - 10/2002
3Drug Therapy (Chemotherapy)
03/2013 - 10/2002
2Neoadjuvant Therapy
04/2017 - 02/2014
2Prostatectomy (Retropubic Prostatectomy)
01/2014 - 03/2002
2Blood Component Removal (Apheresis)
09/2013 - 07/2013
2Aftercare (After-Treatment)
10/2012 - 12/2008
1Brachytherapy
03/2013
1Immunomodulation
01/2006
1Sutures (Suture)
10/2004
1Immunotherapy
10/2004